Nextmove software was founded in 2010 to develop nextgeneration chemoinformatics solutions to pharmaceutical industry problems. Dr roger sayle, ceo of nextmove software added we are excited to be working together with optibrium to combine the matsy technology with stardrop s intuitive interface for compound generation. Digital chemical representations roger sayle nextmove software, cambridge, uk status and future of iupac inchi, bethesda, maryland, usa, wednesday 16th august 2017. Implementing iso 11238 standard compliance with chemaxon tools. Big data is the process of analysing high volume, high velocity data by advanced computational methods that produce actionable knowledge.
Nextmove software s casandra is a server that provides real time alerting of reactive chemical hazards. Leadmine is a dictionarygrammar based approach to entity recognition. Standardized representations of eln reactions for categorization and duplicatevariation identification roger sayle and daniel lowe nextmove software, cambridge, uk. Richard gowers software engineer nextmove software linkedin. Here, we present an investigation of chemical reactions and molecules retrieved from u. Building upon nextmove softwares patsy chemical pattern matching engine, arthor easily outperforms current chemical cartridges, scaling to handle the hundreds of millions of compounds found in next generation chemical databases.
View richard gowers profile on linkedin, the worlds largest professional community. Accelerating graph edit distance search by chemical space enumeration. The combination of these technologies will help guide scientists to quickly identify novel compounds based on matched. Lauren becnel presented the workshop aiassisted data and knowledge acquisition for biomedical researchers 78 march at the european molecular biology laboratoryeuropean bioinformatics institute emblebi on the wellcome genome campus in hinxton, uk. One approach to tackle this is to switch to graph edit distance ged based chemical. Roger sayle chemaxon software solutions and services for.
Rb russell, mas saqi, ra sayle, pa bates, mje sternberg. Jan 15, 2015 dr roger sayle, ceo of nextmove software added we are excited to be working together with optibrium to combine the matsy technology with stardrop s intuitive interface for compound generation. Reactive chemical hazard alerting in pharmaceutical electronic lab notebooks. Nextmove softwares arthor technology named after merlins apprentice pushes the performance limits of chemical database search on current computer hardware. John mayfield 1, roger sayle 1 1 nextmove software ltd whether you are searching a database, filtering sets of compounds, normalising for registration, calculating descriptors, or involved in fragmentbased drug discovery you will need to perform some form of smarts or smartslike match i. Eln reactions for categorization and duplicatevariation identification roger sayle and daniel lowe nextmove software, cambridge, uk th247 acs national meeting, dallas, tx, monday 17th march 2014. Dr matt segall is ceo of optibrium, developers of the stardrop software platform. Sayle 3 nextmove software ltd, innovation centre, unit 23, science park, milton road, cambridge.
The combination of these technologies will help guide scientists to quickly identify novel compounds based on matched molecular series. Optibrium provides elegant software solutions for small molecule design, optimisation and data analysis. See the complete profile on linkedin and discover rogers connections and jobs at similar companies. View roger sayles profile on linkedin, the worlds largest professional community. Verified email at john mitchell reader in translational biology, university of st andrews verified email at standrews. Generating canonical identifiers for glycoproteins and. Corrections to development of a novel fingerprint for. John mayfield abstract eighth joint sheffield conference. Chemical structure representation of inorganic salts and. The primordial soup the vast majority of chemical entities stored in chemical databases and pharmaceutical registration systems are classical small molecules. Roger sayle ceo, nextmove software limited verified email at karol m. Efficient simultaneous matching of multiple smarts using. The server is deployed to an internal network and is configured with an inhouse warning set.
See the complete profile on linkedin and discover richards connections and jobs at similar companies. Digital chemical representations roger sayle nextmove software, cambridge, uk status and future of iupac inchi, bethesda, maryland, usa. Implementing iso standard 11238 compliance with chemaxon tools. As ev experts, we report independently several times a week on our channel on all topics relating. John mayfield abstract eighth joint sheffield conference on. Dr roger sayle, nextmove software, cambridge the explosive growth of purchaseondemand chemical databases, such as enamine real and zinc, is overwhelming traditional chemical database search technologies, whose runtimes scale linearly with database size. The software immediately transformed my business and saved me hours every day. Ubiquitous in published literature, chemical sketches1 combine molecular connection tables with additional drawing elements, free text, and embedded images. Nextmove technologies designs and manufacturers lightweight antenna positioners with low power consumption for both satellite and terrestrial line of sight applications. With modern hardware and efficient algorithms, many classic cheminformatics problems can be. Lauren becnel presented the workshop aiassisted data and knowledge acquisition for biomedical researchers 78 march at the european molecular biology laboratoryeuropean bioinformatics institute emblebi on. A newer system of chemical philosophy roger sayle nextmove software, cambridge, uk rs i ag hemical structure representation. Covid19 is an emerging, rapidly evolving situation. Generating canonical identifiers for glycoproteins and other.
Revising the topliss decision tree share and discover. Roger sayle, richard gowers and john mayfield small organic molecules workshop. The company is located on the cambridge science park in the united kingdom. Nextmove software develops innovative informatics solutions to support strategic decision making in the pharmaceutical and chemical industries. Reaction atom mapping and its application to reaction validation in pharmaceutical elns. Jan 15, 2015 nextmove software roger sayle ceo and founder email. Before starting nextmove software, roger has worked at glaxowellcome now gsk, metaphorics llc and openeye scientific software. Our software provides easy to use tools for acquiring. Although the fields of cheminformatics and retrosynthetic analysis have been well established for a number of decades, there has recently been a large increase in applying methods from the world of big data and predictive analytics to the field of. Implementing iso 11238 standard compliance with chemaxon tools roger sayle nextmove software, cambridge, uk chemaxon user group meeting 2014, budapest, hungary, wednesday 21st may 2014.
Multiple recent studies have focused on unraveling the content of the medicinal chemists toolbox. Using matched molecular series as a predictive tool to. Nextmove software ltd, innovation centre unit 23, science park. For updates, you can follow nextmove software on slideshare, linkedin or twitter. Find all the data submitted to pubchem by nextmove software. Roger sayle read 43 publications contact roger sayle. Efficient simultaneous matching of multiple smarts using the. Optibrium and nextmove software, developers of software and chemoinformatics solutions for drug discovery, today announced an agreement to collaborate on the integration of nextmove softwares matsy technology with optibriums stardrop software suite. Decouvrez qui vous connaissez chez nextmove software, utilisez votre reseau professionnel et faitesvous embaucher.
Before starting nextmove software, roger has worked at glaxowellcome, metaphorics llc and openeye scientific software. Arthor provides fast stateoftheart substructure and chemical similarity search capabilities for ultralarge databases of hundreds of millions of compounds, using smarts optimization, justintime. Every model comes standard with an embedded controller that communicates with on board sensors like gps and compass. Before starting nextmove software, roger worked at glaxowellcome, metaphorics llc and openeye scientific software. Efficient simultaneous matching of multiple smarts using the chemaxon toolkits roger sayle nextmove software ltd cambridge uk 2011 chemaxon ugm, san diego, usa, 28th september 2011. Home nextmove technologies antenna positioning solutions. Whether you are searching a database, filtering sets of compounds, normalising for registration, calculating descriptors, or involved in fragmentbased drug discovery you will need to perform some form of smarts or smartslike match i. Mar 30, 2016 view roger sayles profile on linkedin, the worlds largest professional community. Roger sayle, nextmove software extract, analysis, atom mapping, classification and naming of reactions from pharmaceutical elns andrew hinton, digital science from famine to feast. He gained his phd in computer science at the university of edinburgh. Optibrium and nextmove software announce technology. Before starting nextmove software, roger has worked at. Roger sayle ceo and founder nextmove software linkedin. Recognition of chemical entities in patents using leadmine.
Chemaxon software solutions and services for chemistry. Chemistry and reactions from nonus patents daniel lowe and roger sayle nextmove software. Optibrium and nextmove software announce technology collaboration. I was able to spend a lot less time following up and trying to figure out where my business is. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Roger sayle nextmove software, cambridge, uk th247 acs national meeting, dallas, tx, wednesday 19th march 2014. We used a sophisticated textmining pipeline to extract 1. Chemical structure representation of inorganic salts and mixtures of gases.
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